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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e5e14184952de856d3de5f5fe423529eb62c2b1195080ee507dd2a4828cf3fe1' 
  AND token = '7+pBI37JkDq4MX1HaXbQd54jlRV6jegomQ45F80dDHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}