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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '227e2c862164985afd1ec17b6d2c6091d4e41e68387926b5c1d28c7c8872f81e' 
  AND token = '/jimCtbqeGlbtumxNHEoYtb0f5GfDTFFHrWE1s/Bzek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}