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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e8aa82a571272cea81289f5d65214cfad405f2de3b8a64b898cc506d58f88499' 
  AND token = 'weaCKPVhSL5nzXBE2wRc7eFohiRJoy380iRB75UnWkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}