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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e25313fe8c9d14609c684c03ccbd0d925f609d22272e98904120ff3c656e957d' 
  AND token = 'd1oCScQk2BpSXhHRH11cUS4lMCv8t4LGnyQxSLwUZpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}