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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cda36d1ccf6b6a0f3cf819582f328be5a528dd98deb71077384bcc4ba0f8dd71' 
  AND token = 'fxR+c4MoE09dBdZGUNomYXA5HT05ZQjTSbWT1Q0qPsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}