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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1c0f4db5a8af0f6cd1347bda42b8a8794a8def9ce887122a93f5214bc7d3e549' 
  AND token = 'UQPRP1EB3lvKdNEOjO+G8oOxNFR9qrAuWoRpWZq35ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}