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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7c48212b7a32b5aae5ef515fba1026f841d8bf42dc261f0638b70355dcba8072' 
  AND token = 'G+XiG22n0Ep21ZWeufGgxTYOp86gEnPZQy1Q/4r94v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}