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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f616909dffbdc624a00d6b20bccc1d6d0ac5ebff9009e28418c9d13b5049afd1' 
  AND token = 'NK6FHG/FODrh2lmqf1KjJCXtcdDGi1pz7J/Ft0EK5Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}