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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e19a2ccac2a8166b167fe1434277312aa43bb6b39c6d42c7cd91cbca61089585' 
  AND token = 'pwUq4BPYNyJvBsTbPH2i7T/IQ7c01w9NKe+B3s//TZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}