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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ca1a46221bbfaf4f62ef9079af4f1a2618a1b9319b8c3acff9becb92a164a745' 
  AND token = 'af+ABJwwxlKKUgG7LLf13X5LxoksQ0v19qWk44mPXd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}