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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2a485c2ac4249ab9684656111903421b5107c52ce0f5f4e090ee1d97aa29c59c' 
  AND token = 'TA+roeKuuHCzGMzjxt7uLEqLsAak3VB1WibjZs35Vp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}