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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9ff50d5434d7d116633a10a0a9d2d10c411595a679f523c2c37d176280bf540a' 
  AND token = 'M5i+0nN5/cw6SYnwCGf5VwBC+PofmLbBBdrZeyYB5R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}