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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '28f3a9731f20c19141542d92d89c99b09215022113270b7ee2af6ddc4687dd00' 
  AND token = '9ouEWKSwW7I0h1NPz3mnQ/aVYH8fWXLa1KkhFA28tQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}