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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6c78c4b35b68d050c4779d871db7defdb5280d4bb3d84e12c331db11c07223c2' 
  AND token = 'ARGmpfOlk5uU0g37OhAKnSjShDkD5O+FfJqP31vxprA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}