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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4a1210eb2cbc827bcf59b642a70a1c42241f7a559cca9e494a4429f1746005e2' 
  AND token = 'Ak0VlFNmnMORNY7lUxC+WkebHSUgQ9Pps9pcwP55Yhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}