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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'afb54905181d15dfef860db5ceb5b05ade2f48e3debef5ad3845272121bc1b32' 
  AND token = '0Ec/JMUW853yjtjZ/cKmyPAfLh9PR4jn150dS2Y+c10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}