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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6cfe2501b615ed0381caaa5e0fdff82a64764f9e9c9f496a615d1270da088372' 
  AND token = 'NFBKCp979X72xWNPXO7sxu+p1ZC+6zujdn9bdlZ9nds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}