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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'af0c83b71a6d8721fe9940c96a7d550937b7ca0a47cf541c49e1076f148c31bf' 
  AND token = 'os3qO+442KEw2iAMRPh6ZEk2v+xAIeDU3l4BccM/fW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}