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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a34f0372d017b296e04b5c37f7bef533b4df314274a41e04346b2247e732fc69' 
  AND token = 'zUu6ZbPBEM4bdKgb8pujN0jKUJcnsLW+pej/MjSBey4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}