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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b28f38bd1575d343f7e5da775ccac52439f596fa06b1e3670e04928085ebbbbd' 
  AND token = 's48JNbayTt/U5U2/9V4WH6kloCmubxDZljkMXqFqbZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}