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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd259ae5d40b96460c5f864a78b7aaf02d9be7315a4e6a5c58227a2275b84032f' 
  AND token = 'BSe0Xi5TypaW+LQ7JLOdyD5iffvweOhCf5aseq1cuGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}