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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '81e805d62bcd7505ad6cd9b0506c1b3140a050de93e00b0bc78a711f66c2a06d' 
  AND token = 'SWP3U1ampARHScwOmjjntfWWGmgDLu486ZXApqedrok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}