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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '98451f7271755d61705ce5bf21efd597eee4ee6f8447704a4e64e635cbe7428d' 
  AND token = '2P/mAffGR3NbzoLLmR/wN/LPTOKYoOLaDM/NIZW7ly0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}