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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '377a79b621e24c1856817d440627ba9f60a5e24df9f4615c86ca2e917c29b19b' 
  AND token = 'Do9NxdpKCCS+WJieDUVAwdx1mwjnvq+fVbbN7m7tfGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}