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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '16410f23b35b9caff7720bea8ef5792183a69d6c463b3b86e9a196efbd4fddc3' 
  AND token = '8KhF8g5J96pHf3ny0/d/SnuNlnKm64RbO50V3Ile2t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}