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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'abf08427ca23c04f911d309544fccae4920f28f2bc3a68f194697d8f3c70a4c0' 
  AND token = 'QxDYU0CotsoYuVoKezuMM9VF4cXZknvmeJgo2ZcMZ0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}