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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3535bfe421b11af919885f8b4f845de932a4e03d708e77d69318618c5d3fbcf1' 
  AND token = 'm5TE9X3PxkW3V+DyAC12ogGCmpf2/b7Owoix3kbuUKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}