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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2e98358ecf34571e580350c48880bc7c7a8e02ff9e44cc410748835a41de14d6' 
  AND token = '1EAHOBAUBlmuylDkJ1+meBI9ByukNTTgl9tZot5p61Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}