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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ea5ba4331b5038450dd175fe573288e9deb5f7060b7e11cdff66ed869e515b00' 
  AND token = 'jc2yme7l4WhNj0VmksWiQj6NFMarRr+O5nxseMOVlYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}