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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '64468d01beb7dc6f0506ce44baf7e866a1cfae26106e8dbb5d21011904fadbf0' 
  AND token = 'NfPwiZ2P+TOtpbnzFvuRt5F8BZteZtnV4mxP4Yp1x6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}