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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '21501ad2155c4319c06ac90b6d712e7c5b021560c00bcf09824d86ec85a88171' 
  AND token = 'zOJvx7vn2AxBzuGep5o7FEZ5xRuo0OLY13CvJ4WXZ0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}