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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '429e4e46f3972433687fec13fa27256f4a4094eef8482ebd681a8c338e26aac4' 
  AND token = '2Q7M7ju0Oh7iap68QwLWfoEt9Fn0AaZRmsuWs7lyQis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}