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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22eac0bc62017f2a176cf5bb8b4681e8205eba0f44b47acf8c7cad67eaf10a19' 
  AND token = 'vwMBDYtVRyB8Ut+K6u2Yg2vBadbiiNszCGa9Njepe84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}