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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '11d462781ccf5f67cf2464b408b9de83fd93501aecda57575afdceb25bd01cd4' 
  AND token = 'TVZu4RHY6KuIPne8dQ03eSoc0U0Z9PvoSyDvF0iiZGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}