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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cf6025615217a0b95ed86a4505974ecad69d31066f5abc816bef748b46ebd333' 
  AND token = 'IoWSTXjWqzxgmUr0ASN3ICT7hM7SvfloblV6F5IySdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}