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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5e07385727eead90ccd91c560750823257a0604b4e648964fe0b8413c4f63e90' 
  AND token = 'FBHe3xDS/NYhys1oII6CpSy9LkXP6aTAcRAiQ0Ao+70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}