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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '19f715624e4339f6982ae26d1151be7b167aa106a6d98829a8c02f70a422777a' 
  AND token = 'gC3uRcDpLM0On+msp1CZDTKbrkCUD350/Erm5E7MQRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}