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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '40d81b75411de04e5969a6482149b563147716705ebd38468c9c501a296c273a' 
  AND token = '6DWKxxdw3s+pbGEcHTxNc1BdYWuDDnSQY70sQzdCmX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}