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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '539f0c9908d63585df772abac36af96e95c791f9e31087d1e1b8b613fe547d60' 
  AND token = 'xSFPm9+P5Pa+EOcXKVSe/EK0swOi+yuxvcA3jci6r/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}