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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e4b723ae0c601a151a073962781409da051ea145559670e8bf295049c09dbea3' 
  AND token = '6AatAsgoPmMcAyhUWLouUZfIvvgr+6RmU9npWqHrrko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}