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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'af4ecefcd738cc33d78ce128e6576279c2c8e5cfb91e36ebe3c2d3519df63731' 
  AND token = 'w+hJgfM4NrylyqJ+jW4ktrKsAYctqeCUAKrZKIfYOM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}