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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '728195385595d1fbca12822f027d141b302353a3a2fb7e700a94f20e93a0e377' 
  AND token = 'vI/a8H8grHGjozfeU8QURnQQhFMR9pHjLJGUFhGtQI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}