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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c296248661c2cec1319586ec5e5177ace5c8625776126323508f671e7209e15a' 
  AND token = 'o3trvH7LHr1g+oTgH47vlCXNjh3BLDPzMGQE8KJadao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}