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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dc3b70621e25c0ec102615a604428713a42ae0cb63db84646398ae562700cec0' 
  AND token = '+k7UkVYwS6mBsCnw+s4kGsUYxQkqBsy1X2XcxUNa6uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}