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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b0b7afd7e28debb837923fcb5d4a69c0af7a7b400e758535346633e55dc96077' 
  AND token = 'fsVbZ8BUUign4+3PqRqYqypXtPkj2qW4TLHDPnPnRnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}