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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '21cec749f8476a4055f293a97318f2e33aa5b1c1f366dc43c355bd5f4114c274' 
  AND token = 'e49ELRevp0u/03tMDb3F6ZNr9900C4j4l4GO5IeYIkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}