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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '42f55ca8fce4221f8f31dfa6d29792e1502d0473910bbe6e1aa89589e68979b8' 
  AND token = 'GEfYY4+LYleQewmDq13CWymCkmWU1PtXOG44R76lHFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}