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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8f4fadd7a1a9500b9819787288ee52b9d8ee18e952f229def93a7cd0d83a135b' 
  AND token = 'D47kXMAxnpK7/CU/0L6RMLkVhBX3xq3A7AlxULXkk6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}