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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bc3e1bbda7a06c38a7a419437a494d62bfc324965912ee475e4caf9bfa8061e2' 
  AND token = 'x6A27yOP2wX9NGMG3WuF8XkyrOSsBOCExRJzXnTcxV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}