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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a46db6ff7609b364981ce8e5a4be6a37cadd8345f763123302b11a929f1e961e' 
  AND token = 'SHaq3paygkBuxeV1yhpHs/0iwg9j8mDNzBCxHFDFQE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}